GPT-5
GPT-5 lowers the cost of cell-free protein synthesis
An autonomous lab combining OpenAI’s GPT-5 with Ginkgo Bioworks’ cloud automation cut cell-free protein synthesis costs by 40% through closed-loop experimentation.
Inside OpenAI’s in-house data agent
How OpenAI built an in-house AI data agent that uses GPT-5, Codex, and memory to reason over massive datasets and deliver reliable insights in minutes.
Retiring GPT-4o, GPT-4.1, GPT-4.1 mini, and OpenAI o4-mini in ChatGPT
On February 13, 2026, alongside the previously announced retirement of GPT‑5 (Instant, Thinking, and Pro), we will retire GPT‑4o, GPT‑4.1, GPT‑4.1 mini, and OpenAI o4-mini from ChatGPT. In the API, there are no changes at this time.
Measuring AI’s capability to accelerate biological research
OpenAI introduces a real-world evaluation framework to measure how AI can accelerate biological research in the wet lab. Using GPT-5 to optimize a molecular cloning protocol, the work explores both the promise and risks of AI-assisted experimentation.
Increasing revenue 300% by bringing AI to SMBs
Discover how Podium used OpenAI’s GPT-5 to build “Jerry,” an AI teammate driving 300% growth and transforming how Main Street businesses serve customers.
How Scout24 is building the next generation of real-estate search with AI
Scout24 has created a GPT-5 powered conversational assistant that reimagines real-estate search, guiding users with clarifying questions, summaries, and tailored listing recommendations.
Inside JetBrains—the company reshaping how the world writes code
JetBrains is integrating GPT-5 across its coding tools, helping millions of developers design, reason, and build software faster.
GPT-5 and the future of mathematical discovery
UCLA Professor Ernest Ryu and GPT-5 solved a key question in optimization theory, showcasing AI’s role in accelerating mathematical discovery.
Early experiments in accelerating science with GPT-5
OpenAI introduces the first research cases showing how GPT-5 accelerates scientific progress across math, physics, biology, and computer science. Explore how AI and researchers collaborate to generate proofs, uncover new insights, and reshape the pace of discovery.
Notion’s rebuild for agentic AI: How GPT‑5 helped unlock autonomous workflows
Discover how Notion rebuilt its AI architecture with GPT-5 to create autonomous agents that reason, act, and adapt across workflows. Learn how this shift unlocked smarter, faster, and more flexible productivity in Notion 3.0.
Addendum to GPT-5 System Card: Sensitive conversations
This system card details GPT-5’s improvements in handling sensitive conversations, including new benchmarks for emotional reliance, mental health, and jailbreak resistance.
Consensus accelerates research with GPT-5 and Responses API
Consensus uses GPT-5 and OpenAI’s Responses API to power a multi-agent research assistant that reads, analyzes, and synthesizes evidence in minutes—helping over 8 million researchers accelerate scientific discovery.
With GPT-5, Wrtn builds lifestyle AI for millions in Korea
Wrtn scaled AI apps to 6.5M users in Korea with GPT-5, creating ‘Lifestyle AI’ that blends productivity, creativity, and learning—now expanding across East Asia.
Shipping smarter agents with every new model
Discover how SafetyKit leverages OpenAI GPT-5 to enhance content moderation, enforce compliance, and outpace legacy safety systems with greater accuracy .
Scaling accounting capacity with OpenAI
Built with OpenAI o3, o3-Pro, GPT-4.1, and GPT-5, Basis’ AI agents help accounting firms save up to 30% of their time and expand capacity for advisory and growth.
Introducing GPT-5 for developers
Introducing GPT-5 in our API platform—offering high reasoning performance, new controls for devs, and best-in-class results on real coding tasks.
GPT-5 and the new era of work
GPT-5 is OpenAI’s most advanced model—transforming enterprise AI, automation, and workforce productivity in the new era of intelligent work.
Coding and design with GPT-5
Learn how GPT-5 unlocks new possibilities in coding and design.
Creative writing with GPT-5
Learn how GPT-5 assists with creative writing.
Medical research with GPT-5
Learn how GPT-5 is used for medical research.